The association between weight gain up to midlife, 30-year mortality, and quality of life in older men.

A recent editorial 1 and articles in the Archives investigated the complex relationships between obesity, mortality, and disability, and studies that take into account the dynamic history of body weight over one’s life span were called for. In the follow-up of the Helsinki Businessmen Study, we have combined these aspects (weight gain in midlife, mortality, and healthrelated quality of life [HRQOL] in old age). We report herein the extended follow-up (now up to 30 years) of these relationships.